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ALPS Medical Breakthroughs ETF SBIO
Historical return decomposition and an investable replication portfolio, using data through 2026-10-09.
Fund and replication metrics
| Measure | SBIO | Replication |
|---|---|---|
| Annualized growth | 4.5% | 5.8% |
| Annualized volatility | 32.6% | 23.1% |
| Sharpe ratio | 0.30 | 0.36 |
| Maximum drawdown | 51.5% | 40.2% |
| Replication fit (R²) | 0.56 · Tracking error 21.5% | |
Replication portfolio
The published portfolio below is the investable basket used to model SBIO’s historical return behavior.
| Ticker | Building block | Weight |
|---|---|---|
| IWC | Micro Cap | 96.9% |
| VBK | Small-Cap · Growth | 3.1% |